PICSI- What it is, When it is needed, and Procedure
Physiological Intracytoplasmic Sperm Injection (PICSI) for IVF treatment comes under state-of-the-art facilities. When you visit fertility clinics for your treatment, it's vital to ensure the clinic has the technology and equipment to conduct procedures for a high success rate. Bloom IVF is one of the top options for using the latest technology equipment for IVF treatment. PICSI IVF is one of those; let's understand in detail:
What Is PICSI?
PICSI, or Physiological Intracytoplasmic Sperm Injection, is the latest innovative technique used for ART-Assisted Reproductive Technology. It helps in improving the success rate of IVF treatment more than traditional methods. It is a technology-modified form of ICSI procedure that is used for patients who need ICSI. Generally, men have a high degree of immature sperm that might have high levels of damaged DNA. This immature sperm, when selected for insemination, can lead to pregnancy loss or low-quality embryos. Using the PICSI IVF technique, it becomes more efficient to select mature sperm for injection for high-success IVF treatment.
Who Requires PICSI?
When you visit a fertility clinic, a semen assessment test is conducted to check the quality and other details. If the HBA score is less than 65%, it indicates a reduced level of mature sperm. So, PICSI IVF is recommended. In addition, it is also recommended to:
- Women above 38.
- Those who have failed to fertilize eggs using ICSI.
- When the development of the embryo is of low quality,
- With a history of multiple abortions.
- If % of spermatozoa with high PICSI DNA fragmentation index (DFI).
What Is The Procedure Of PICSI?
The PICSI procedure for IVF or IUI treatment is performed in several steps such as follows:
- A substance called "Hyaluronan" coated dish is prepared, which is a component found in the cumulus cells. It mimics the natural environment of quality eggs, thus helping to select the mature sperm. There are ready-to-use PICSI dishes available that are used most commonly.
- A semen sample collected from the male partner undergoes processing for the separation of sperm from seminal fluid and debris.
- This sample is then placed on a coated dish. Mature sperms bind with Hyaluronan, while immature sperms will not.
- Under the microscope or embryoscope, sperms that have bonded successfully with a coated dish are checked for and used for IVF treatment.
- The mature selected sperms are then selected to be injected via a needle into the egg cytoplasm for ICSI (Intracytoplasmic Sperm Injection).
Indications of PICSI
When sperm quality is low or compromised, PICSI is indicated. Couples having reduced sperm motility, high levels of PICSI DNA fragmentation, and morphology abnormalities benefit from the technique. It helps in improving the chances of embryo development and fertilization for IVF.
Is PICSI Better Than ICSI?
PICSI is a technique used for identifying mature sperm, while ICSI is a technique for infertility treatment that involves injecting sperm into embryos. The difference between ICSI and PICSI is that PICSI is used in the procedure of ICSI to amplify its success rate, especially if the previous IVF procedure without PICSI failed. PICSI is used only in certain cases for the ICSI process.
PICSI and IVF Treatment Success
PICSI is a technique for selecting mature sperm that significantly improves the success rate for IVF. In some cases, if IVF is not successful or there are certain conditions indicating low success for IVF, PICSI is used to increase the chances of IVF treatment success.
Bloom IVF For PICSI
Bloom IVF is the finest fertility clinic in India, providing fertility treatments for couples. From high-end equipment to well-trained staff, the clinic has everything for you. We use efficient methods after high assessment to ensure an increased success rate. With our affordable treatment and the latest techniques, you can have a chance of becoming a parent. Whether it's IVF treatment or diagnosis for reproductive issues, we can help. We suggest PICSI for couples to increase their chances of IVF.