Signs and symptoms of infertility
Age
Painful sex
Menorrhagia means heavy bleeding
Hormonal changes
Underlying medical conditions
Obesity
Natural Trying period more than 1 year
After trying of simple treatment like 3 cycles of IUI
low sperm count or AMH
problems with ovulation due to conditions like polycystic ovary syndrome
problems with the fallopian tubes means blocked or damaged Or sterilised
endometriosis
a wish to avoid passing on inherited geneticdisorders to your children
People who have cancer can go ahead with fertility preservation by freezing eggs and sperms before chemotherapy and radiotherapy, as chemotherapy and radiotherapy can harm your fertility. These eggs or sperm can be thawed later and used in IVF once the cancer treatment is over.
No .. it's not 100% The success rates depends on various factors like age , underlying reason for IVF like endometriosis , severe low sperm count or zero sperm count and quality of eggs and sperms.
Age less than 35 usually success rate is. 50 to 60 percent
Age 35 to 40 yrs ... Around 50 percent with the use of technology
More than 40 yrs success rate is around 40%
Young age who has tried naturally for more than 1 year
Patent (open) fallopian tubes
Cervical factor – abnormalities of cervical mucus or cervical canal
Some ovulatory abnormalities – irregular menstrual cycles, PCOS
Absence of or minimal endometriosis (Mild or Stage I-II Endometriosis)
Mostly normal sperm evaluation
Complete absence of sperm in the male (azoospermia) requiring donor sperm IUI.
Risk of multiple birth
Threatened abortions
Pretem birth means early delivery
Low birth weight babies
Anaemia
Gestational diabetes mellitus
Birth defects
Twin twin transfusion syndrome
Post partum hemorrhage
Pregnancy induced hypertension
Antioxidants .. means oral medications
Hormonal therapy
Surgical interventions for azoospermia means zero sperms like TESA MESA
PESA and MTeSE
Use of technology in IVF like ICSI Microfluidics IMSI PICSI MACS
Abnormal sperm production due to probleem like undescended testicles, geneticdefects, health problems such as diabetes, or infections such as chlamydia, gonorrhea, mumps or HIV. Enlarged veins in the testes (varicocele) also can affect the quality of sperm.
Problems with the delivery of sperm due to sexual problems, such as premature ejaculation; certain geneticdiseases, such as cystic fibrosis; structural problems, such as a blockage in the testicle; or damage or injury to the reproductive organs.
Overexposure to certain environmental factors, such as pesticides and other chemicals, and radiation. Cigarette smoking, alcohol , anabolic steroids, and certain medications to treat bacterial infections, high blood pressure and depression also can affect fertility.
Frequent exposure to heat, such as in saunas or hot tubs, or chimney factories or excessive riding of bikes can raise body temperature and may affect sperm production.
Damage related to cancer and its treatment, including radiation or chemotherapy.
Anovulation that may be because of A hormone imbalance , A tumor or cyst
Eating disorders such as anorexia or bulimia , Alcohol or drug use,.Thyroid gland problems , Excess weight, Stress
Intense exercise that causes a significant loss of body fat Extremely brief menstrual cycles
Pelvic inflammatory disease which may cause blockage of fallopian tubes Polyps in the uterus, endometriosis or fibroids
Chronic medical illness
previous ectopic (tubal) pregnancy, A birth defect
This means the there is some problem like quality or morphology with either the egg or sperm.
Certain technologies like Assisted laser hatching , ICSI , IMSI , Poloscope or spindle check , embryoscope can be used to overcome such situations .
A woman’s best reproductive years are between 20 and 30
Fertility gradually declines in the 30s, specifically after age 35.
Each month that she tries, a healthy, fertile 30-year-old woman has a 10 to 20 % chance of getting pregnant. That means that for every 100 fertile 30-year-old women trying to get pregnant in 1 cycle, 10-20 will be successful and the others will have to try again. By age 40, a woman’s chance is less than 5% per cycle, so fewer than 5 out of every 100 women are expected to be successful each month.
So in short as the age advances the number of eggs goes down and the quality of eggs goes down
Endometriosis is an entity where the endometrial tissue of the uterus is found elsewhere outside the uterus - ovaries , Fallopian tube , peritoneum intestines etc
Woman’s most fertile time - when she ovulates - 14 days before her period date.
28 days cycle - 14 day - planned relation on alternate days - 12,14,16
35 days cycle - 21 day- planned relation on alternate days - 19, 21 , 23
If u do not want to use your stored embryos , you can give consent to discard , donate the embryos for research , embryo adoption.
Insurance plans do not cover infertility treatment but emi facilities and instalment payments make it easier options for patients to avail the facilities.
Steps of IVF :
1. Ovarian stimulation - to develop good number of follicles - eggs
2. Egg pick up
3. Fertilisationof the egg with the sperm by Ivf / ICSI
4. Formation of embryo
5. Embryo transfer in the uterus
Difference between IUI AND IVF
IUI simple non invasive , doesn’t require Anesthesia , husbands semen is taken and instilled in the uterine cavity . Fertilisation occurs in the body .
IVF is an invasive procedure - involves formation of the embryos outside the body - egg pick up - fertilisation outside by IVF / ICSI .
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